Seventeen-year-old Bianca Piper may not be the prettiest girl in her high school, but she has a loyal group of friends, biting wit, and a spot-on BS detector. She's also way too smart to fall for the charms of a man-slut and slimy school hottie Wesley Rush, who calls Bianca the Duff - the designated ugly fat friend - of her crew.
Seventeen-year-old Bianca Piper is smart, cynical, loyal - and well aware that she's not the hot one in her group of friends. But when high-school jock and all round moron Wesley Rush tells her she's a DUFF - a Designated, Ugly Fat Friend - Bianca does not the see funny side. She may not be a beauty but she'd never stoop so low as to go anywhere near the likes of Wesley ... Or would she?